Manny Pacquiao to Lose in 2012 Boxing Match with Juan Manuel Marquez?

For the first time in seven years, Manny Pacquiao will lose a boxing match in 2012.

A boxing analyst from Sports Illustrated predicted that Manny will lose to Juan Manuel Marquez.

Pacquiao and Marquez’s careers have become as intertwined as Sugar Ray Robinson and Jake LaMotta, Muhammad Ali and Joe Frazier.

The analyst said that since the mega-fight of Pacquiao against undefeated American Floyd Mayweather Jr. will not be possible until June, a fourth fight with Marquez is the only natural option.

Mayweather will be serving a jail sentence of 90 days in prison.